|
KMID : 1134820190480090961
|
|
Journal of the Korean Society of Food Science and Nutrition
2019 Volume.48 No. 9 p.961 ~ p.966
|
|
|
Determination of Dimethyl Dicarbonate in Food and Beverage with HPLC-PDA and LC-MS
|
|
Shin Jae-Wook
Kim Jung-Bok
|
|
|
Abstract
|
|
|
|
A sensitive and simple analytical method to identify derivatives of dimethyl dicarbonate (DMDC) residues in fruit beverage and wine was developed and then validated using HPLC-PDA. The calibration curve was obtained from 1 μg/mL to 200 μg/mL with a satisfactory correlation coefficient of 0.999. The limit of detection and limit of quantitation for a derivative of DMDC were 0.30 μg/mL and 0.92 μg/mL, respectively. The recoveries of derivatives of DMDC from spiked samples at levels of 10∼200.0 μg/mL ranged from 92.8 to 101.0% with the relative standard deviation between 0.9 and 1.9%. The measurement of uncertainty of the developed HPLC method for identifying derivatives of DMDC was based on the analytical process and quantification. These results show that the method developed in this study is appropriate for DMDC identification and it can be used to maintain the safety of food products that contain DMDC residues.
|
|
|
KEYWORD
|
|
|
derivative dimethyl dicarbonate, DMDC, method validation, HPLC-PDA, LC-MS
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|